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Creative Bio-Peptides Inc.

Creative Bio-Peptides Inc.

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RECEPTIDES

We believe the smart way of looking for new medicines is by learning from nature. We have observed that certain viruses have “learned” how to control host immunity in an elegant way that provides a balanced modulation of immunity without suppressing beneficial host immune function(s).  Identifying such naturally-occurring receptor-targeting sequences that engage the human immune system provides a rational basis for drug development.

We have discovered, from HIV, innate immune modifying  peptides that are both highly potent and have a nuanced receptor bias that modulates multiple biological effects that would be difficult, if not impossible, to design or discover by typical drug screening methods. Modeled on their viral counterparts, the peptides we create have the highly desired pharmacologic property of being partial antagonists that balance excess immune responses without completely shutting them down, while activating cellular repair processes.

We call our oral peptides Receptides to indicate their receptor mediated actions that modulate a cluster of innate immune chemokine receptors (CCR2/5/8,CXCR4).  Chemokine receptors act on both immune cells and neurons to sculpt neuronal connections and synapses.  Blocking these receptors has been shown to inhibit the neurotoxic effects of microglial and astrocyte activation to restore synapses and dendritic arbor to stop, even reverse, the dendritic damage that underlies dementia’s, neuropathies,  brain injury, and possibly opioid use disorders.

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Latest News

  • RAP-103 Inhibits Opioid-derived Dependence, Withdrawal and Respiratory Depression  Jul 19, 2022
  • RAP-103 Benefits in Pain Published Jul 14, 2022
  • BioHealth Innovation Press Release Features Creative Bio-Peptides Nov 30, 2021
  • A Conversation with CBO Michael Simon Apr 8, 2021
  • NIH SBIR AWARD FOR SYNAPSE PROTECTING TREATMENTS FOR ALZHEIMER’S DISEASE Sep 28, 2020
  • CREATIVE BIO-PEPTIDES RECEIVES NIH HEAL AWARD FOR OPIOID ABUSE DISORDERS Jan 20, 2020
  • CREATIVE BIO-PEPTIDES and LEIDOS AWARDED US DOD CONTRACT Jan 18, 2020

Read more news

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Creative Bio-Peptides Inc.

Rockville, MD
USA  20854

  • LinkedIn

  • RAP-103 Inhibits Opioid-derived Dependence, Withdrawal and Respiratory Depression  Jul 19, 2022
  • RAP-103 Benefits in Pain Published Jul 14, 2022
  • BioHealth Innovation Press Release Features Creative Bio-Peptides Nov 30, 2021
  • A Conversation with CBO Michael Simon Apr 8, 2021
  • NIH SBIR AWARD FOR SYNAPSE PROTECTING TREATMENTS FOR ALZHEIMER’S DISEASE Sep 28, 2020
  • CREATIVE BIO-PEPTIDES RECEIVES NIH HEAL AWARD FOR OPIOID ABUSE DISORDERS Jan 20, 2020
  • CREATIVE BIO-PEPTIDES and LEIDOS AWARDED US DOD CONTRACT Jan 18, 2020

Read more news

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